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Publication | Open Access

Shiga Toxin Receptor Gb3Cer/CD77: Tumor-Association and Promising Therapeutic Target in Pancreas and Colon Cancer

DOIFull Paper Access

77

Citations

42

References

2009

Year

Ute Distler, Jamal Souady, Marcel Hülsewig, Irena Drmić Hofman, Jörg Haier, Alexander W. Friedrich, Helge Karch, N. Senninger, Klaus Dreisewerd, Stefan Berkenkamp,
PLoS ONE

Abstract

Enhanced expression of Gb3Cer/CD77 in most pancreatic and colon adenocarcinomas prompts consideration of Shiga toxin, its B-subunit or B-subunit-derivatives as novel therapeutic strategies for the treatment of these challenging malignancies.

References

YearCitations

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