Bioinformatics · 2013 · 315 citations · 8 references
Life SciencesBioinformaticsMolecular BiologyGenomic Data AnalysisGenomicsSequence AnalysisDna SequencingGenome SequencingGenomic Data VisualizationNext-generation SequencingData Management PlatformsModular Platform ArchitectureNext-generation Sequencing Data AnalysisOpen Data ManagementSupplementary Data Management
Abstract Summary: NGSUtils is a suite of software tools for manipulating data common to next-generation sequencing experiments, such as FASTQ, BED and BAM format files. These tools provide a stable and modular platform for data management and analysis. Availability and implementation: NGSUtils is available under a BSD license and works on Mac OS X and Linux systems. Python 2.6+ and virtualenv are required. More information and source code may be obtained from the website: http://ngsutils.org. Contact: yunliu@iupui.edu Supplemental information: Supplementary data are available at Bioinformatics online.
8
The Sequence Alignment/Map format and SAMtools
Heng Li, Alec Wysoker, Tim Fennell et al. · Bioinformatics · 2009 · 67.5K citations · Full text
BEDTools: a flexible suite of utilities for comparing genomic features
Aaron R. Quinlan, Ira M. Hall · Bioinformatics · 2010 · 30.4K citations · Full text
The variant call format and VCFtools
Petr Danecek, Adam Auton, Gonçalo R. Abecasis et al. · Bioinformatics · 2011 · 17.8K citations · Full text
Mapping and quantifying mammalian transcriptomes by RNA-Seq
A Mortazavi, Brian A. Williams, Kenneth McCue et al. · Nature Methods · 2008 · 14.3K citations
The Human Genome Browser at UCSC
W. James Kent, Charles W. Sugnet, Terrence S. Furey et al. · Genome Research · 2002 · 10.9K citations · Full text