The novel, peripherally restricted GABAB receptor agonist lesogaberan (AZD3355) inhibits acid reflux and reduces esophageal acid exposure as measured with 24-h pHmetry in dogs

Control of transient lower oesophageal sphincter relaxations and reflux by the GABA _B agonist baclofen in patients with gastro-oesophageal reflux disease

Q Zhang, A. Lehmann, R.S. Rigda et al. · Gut · 2002 · 352 citations · Full text

Medicine, Pharmacology, Pharmacotherapy +17

Control of transient lower esophageal sphincter relaxations and reflux by the GABAB agonist baclofen in normal subjects

Ilmars Lidums, Anders Lehmann, Helen Checklin et al. · Gastroenterology · 2000 · 326 citations · Full text

Medicine, Pharmacology, Pharmacotherapy +16

Baclofen decreases acid and non‐acid post‐prandial gastro‐oesophageal reflux measured by combined multichannel intraluminal impedance and pH

Marcelo F. Vela, Radu Țuțuian, Philip O. Katz et al. · Alimentary Pharmacology & Therapeutics · 2003 · 319 citations

Medicine, Pharmacology, Pharmacotherapy +16

Effect of the GABA _B agonist baclofen in patients with symptoms and duodeno-gastro-oesophageal reflux refractory to proton pump inhibitors

G.H. Koek · Gut · 2003 · 297 citations · Full text

Medicine, Pharmacology, Pharmacotherapy +16

Determinants of gastro-oesophageal reflux perception in patients with persistent symptoms despite proton pump inhibitors

F. Zerbib, Arnaud Duriez, Sabine Roman et al. · Gut · 2007 · 173 citations

Medicine, Clinical Sciences, Pharmacotherapy +14