Arthroscopy The Journal of Arthroscopic and Related Surgery · 2010 · 36 citations · 18 references
MedicineOrthopaedic SurgeryOrthopedic SurgeryOrthopedicsSurgical PathologyBone PathologyJoint SurgeryBioabsorbable Fixation DevicesHistologic ExaminationKnee Osteochondral LesionsOsteochondrosis Dissecans
PURPOSE: The purpose was to evaluate the effect of fixation of detached free fragments of osteochondritis dissecans (OCD) (International Cartilage Repair Society OCD IV) on not only the clinical outcome, including functional and radiographic assessment, but also postoperative second-look arthroscopic and histologic evaluation. METHODS: Nine International Cartilage Repair Society OCD IV fragments were fixed with bioabsorbable pins made of poly-L-lactic acid after curettage of the bed and bone grafting. In 4 cases with severe cartilage damage in the fragments, after resection of the damaged part, trimmed fragments were fixed and osteochondral autologous transplantation was performed to cover the remaining defects. The follow-up period was at least 2 years (range, 2 to 3 years). Lysholm score and computed tomography (CT)/magnetic resonance imaging (MRI), second-look arthroscopy, and biopsy findings were examined postoperatively. RESULTS: All patients ultimately could return to previous sports activity, and the mean postoperative Lysholm score was 97 (range, 90 to 100). At 6 months, CT/MRI scans showed complete union and smooth continuity of articular surface in all cases. Second-look arthroscopy in 7 cases showed that fixed fragments were stable and that there were no progressive degenerative changes in the cartilage. Postoperative histologic examination in 4 cases showed almost normal cartilage from surface to bottom in terms of viability and quality. In addition, new bone trabeculae were covering dead bone trabeculae, which is called creeping substitution. CONCLUSIONS: Our study shows good short-term clinical results, as well as confirmation of healing on CT/MRI and second-look arthroscopy. LEVEL OF EVIDENCE: Level IV, therapeutic case series.
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Autologous Chondrocyte Transplantation
Lars Peterson, Mats Brittberg, Illka Kiviranta et al. · The American Journal of Sports Medicine · 2002 · 872 citations
Gregory C. Berlet, Anthony Mascia, Anthony Miniaci · Arthroscopy The Journal of Arthroscopic and Related Surgery · 1999 · 166 citations