Archives of Disease in Childhood · 1962 · 39 citations · 17 references
Public HealthNeurologyPediatricsChild DevelopmentInfant HealthMicronutrient DeficiencyChild Micronutrient DeficiencyEarly-life NutritionMicronutrient Deficiency In ChildhoodNutrition In Neurologic DisordersNutritional DeficienciesNutritional Deficiency DisordersDietary Deficiency DisordersInfantile Thiamine DeficiencyNeonatal ConvulsionsPyridoxine Metabolism
The association of dietary pyridoxine deficiency and convulsions was first noted in animal experi-ments by Chick, El Sadr and Worden (1940). An analogous situation in humans was recognized when Snyderman, Carretero and Holt (1950) des-cribed the onset of seizures in a mentally retarded child whose diet lacked this vitamin. Shortly afterwards, an outbreak of convulsions in young infants in the United States was shown to be due to the low pyridoxine content in their diet (Coursin,
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