Concepedia

Mice deficient for cytosolic thymidine kinase gene develop fatal kidney disease

Vasily N. Dobrovolsky, Thomas J. Bucci, Robert H. Heflich, John Desjardins, Frank C. Richardson

Molecular Genetics and Metabolism · 2003 · 58 citations · 39 references

DOI

Concepts

References

39

Phosphorylation of 3'-azido-3'-deoxythymidine and selective interaction of the 5'-triphosphate with human immunodeficiency virus reverse transcriptase.

P A Furman, James A. Fyfe, M H St Clair et al. · Proceedings of the National Academy of Sciences · 1986 · 1.3K citations · Full text

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HPRT-deficient (Lesch–Nyhan) mouse embryos derived from germline colonization by cultured cells

Martin Hooper, Kate Hardy, Alan H. Handyside et al. · Nature · 1987 · 1.2K citations

, , +16

Male–female differences in fertility and blood pressure in ACE-deficient mice

John H. Krege, Simon W. M. John, Laura L. Langenbach et al. · Nature · 1995 · 647 citations

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Mutant mitochondrial thymidine kinase in mitochondrial DNA depletion myopathy

Ann Saada, Avraham Shaag, Hanna Mandel et al. · Nature Genetics · 2001 · 621 citations

, , +14

A potential animal model for Lesch–Nyhan syndrome through introduction of HPRT mutations into mice

Michael R. Kuehn, Allan Bradley, Elizabeth J. Robertson et al. · Nature · 1987 · 498 citations

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