Hematopoiesis Controlled by Distinct TIF1γ and Smad4 Branches of the TGFβ Pathway

Mechanism of activation of the TGF-β receptor

Jeffrey L. Wrana, Liliana Attisano, Rotraud Wieser et al. · Nature · 1994 · 2.3K citations

Life Sciences, Cell Biology, Molecular Biology +9

KAP-1, a novel corepressor for the highly conserved KRAB repression domain.

Joshua R. Friedman, William J. Fredericks, D. E. Jensen et al. · Genes & Development · 1996 · 675 citations · Full text

Life Sciences, Genetics, Molecular Biology +16

Inhibition of Transforming Growth Factor (TGF)-β1–Induced Extracellular Matrix with a Novel Inhibitor of the TGF-β Type I Receptor Kinase Activity: SB-431542

Nicholas J. Laping, Eugene T. Grygielko, Anil Mathur et al. · Molecular Pharmacology · 2002 · 650 citations

Life Sciences, Molecular Biology, Pharmacology +16

A possible involvement of TIF1 alpha and TIF1 beta in the epigenetic control of transcription by nuclear receptors.

Bertrand Le Douarin, Anders Lade Nielsen, Jean‐Marie Garnier et al. · The EMBO Journal · 1996 · 540 citations · Full text

Life Sciences, Genetics, Molecular Biology +14

Targeting histone deacetylase complexes via KRAB-zinc finger proteins: the PHD and bromodomains of KAP-1 form a cooperative unit that recruits a novel isoform of the Mi-2α subunit of NuRD

D. Schultz, Josh R. Friedman, Frank J. Rauscher · Genes & Development · 2001 · 527 citations · Full text

Life Sciences, Genetics, Molecular Biology +17