Journal of Bone and Joint Surgery - British Volume · 2000 · 16 citations · 22 references
Natural SciencesOrthopaedic SurgerySurgeryBiocompatibilityCeramic MaterialsOrthopaedic BiomaterialsBioceramicsBone TissueCeramic BiomaterialsImplant MaterialsImplantable BiomaterialsPorous CeramicsCeramic Bone SubstitutesCeramic Implant MaterialsCeramic ImplantsPorous BiomaterialsPorous Bone SubstitutesPorous Ceramic MaterialsPorous Implant MaterialsPorous Structures
We evaluated the efficacy and biocompatibility of porous apatite-wollastonite glass ceramic (AW-GC) as an intramedullary plug in total hip replacement (THR) for up to two years in 22 adult beagle dogs. Cylindrical porous AW-GC rods (70% porosity, mean pore size 200 microm) were prepared. Four dogs were killed at 1, 3, 6 and 12 months each and six at 24 months after implantation. Radiological evaluation confirmed the efficacy of porous AW-CG as an intramedullary plug. Histological evaluation showed osteoconduction at one month and resorption of the porous AW-GC, which was replaced by newly-formed bone, at 24 months. Our findings indicate that porous AW-GC can be used clinically as an intramedullary plug in THR.
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