Concepedia

A trifluoromethylphenyl diazirine-based SecinH3 photoaffinity probe

Barbara Albertoni, Jeffrey S. Hannam, Damian Ackermann, Anton Schmitz, Michael Famulok

Chemical Communications · 2011 · 18 citations · 26 references

DOI

Concepts

Abstract

The synthesis of a trifluoromethylphenyl diazirine photoaffinity probe of the cytohesin inhibitor SecinH3 is described. The probe exhibits improved labelling efficiency over a benzophenone-based probe and thus is more suitable for photoaffinity labelling in complex biological samples.

References

26

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