Nickel/BPh₃‐Catalyzed Alkynylcyanation of Alkynes and 1,2‐Dienes: An Efficient Route to Highly Functionalized Conjugated Enynes

Abstract

Adding across: A C(sp)C(sp) bond of alkynyl cyanides is activated by nickel/Lewis acid catalysis derived from [Ni(cod)2] and BPh3, and the alkynylcyanation reaction of alkynes and 1,2-dienes is achieved by the binary catalysis for the first time to give a range of functionalized conjugated enyne molecules with defined stereo- and regioselectivities. Supporting information for this article is available on the WWW under http://www.wiley-vch.de/contents/jc_2002/2008/z704095_s.pdf or from the author. Please note: The publisher is not responsible for the content or functionality of any supporting information supplied by the authors. Any queries (other than missing content) should be directed to the corresponding author for the article.