Concepedia

A receptor for phosphatidylserine-specific clearance of apoptotic cells

Valerie A. Fadok, Donna L. Bratton, David M. Rose, Alan Pearson, R. Alan B. Ezekewitz, Peter M. Henson

Nature · 2000 · 1.5K citations · 53 references

DOI

Concepts

References

53

Exposure of phosphatidylserine on the surface of apoptotic lymphocytes triggers specific recognition and removal by macrophages

Valerie A. Fadok, Dennis R. Voelker, P A Campbell et al. · The Journal of Immunology · 1992 · 3.3K citations

, , +13

Macrophages that have ingested apoptotic cells in vitro inhibit proinflammatory cytokine production through autocrine/paracrine mechanisms involving TGF-beta, PGE2, and PAF.

Valerie A. Fadok, Donna L. Bratton, Anatole Konowal et al. · Journal of Clinical Investigation · 1998 · 3.1K citations · Full text

, , +17

Early redistribution of plasma membrane phosphatidylserine is a general feature of apoptosis regardless of the initiating stimulus: inhibition by overexpression of Bcl-2 and Abl.

Séamus J. Martin, Chris Reutelingsperger, Anne J. McGahon et al. · The Journal of Experimental Medicine · 1995 · 2.9K citations · Full text

, , +12

Membrane protein structure prediction

Gunnar von Heijne · Journal of Molecular Biology · 1992 · 1.7K citations

, , +12

Vitronectin receptor-mediated phagocytosis of cells undergoing apoptosis

John Savill, Ian Dransfield, Nancy Hogg et al. · Nature · 1990 · 855 citations

, , +12