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Effect of exposure to toxic gas on the population of Bhopal: Part II--Respiratory impairment.
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1988
Year
Air QualityExposure AssessmentRespiratory ImpairmentRestrictive Pulmonary DefectRespiratory ToxicologyEnvironmental ExposureEnvironmental HealthSimple Spirometric LesuToxicologyPublic HealthAllergyEnvironmental Lung DiseasesOccupational Lung DiseasesHuman ExposurePulmonary MedicinePulmonary DiseaseEpidemiologyPart IiInhalation ToxicologyPulmonary PhysiologyLung MechanicsEnvironmental ToxicologyAir PollutionHuman PopulationMedicine
produced three patterns of respirato ry disorders as indicated by simple spirometric lesU. Bro nchial obslnlction was re corded in 3.7% male and 3.6% female po?Jation respecti vely, while restrictive pulmonary defect was noticed in 13.4% cases. The combined obstructive-cum-restrictive ventilatory disorder was observed in 22.2% population. The possible mechanis ms invoJ\'i;d in the pulmonary dysfunction induced by toxic gas are discussed. Exposure to the toxic gas caused various pulmonary abnormalities resulting in a number of respiratory symptoms, viz. cough, dyspnoea, chest pain. etc. in the population of Bhopal. No epidemiological srudy is so far reported in the lit erature involving exposure 10 the human population to the toxic gas. Some sOld ies had been conducted with isocyanates' - s. Cumu lative effect on lung function of the persons exposed to toluene diisocyanate (WI) has been report cd - 11. Significant decrease occurred in FVC, FEV PEFR, FEF of VC on account of W] expo IUre'2-'S. A recent sOldy' has suggested that infil trated lung diseases with pulmonary function abnor malities may occur in workers exposed to WI. MIIteriais and Methods