Publication | Closed Access
Mesoporous Silica Nanoparticles Facilitate Delivery of siRNA to Shutdown Signaling Pathways in Mammalian Cells
235
Citations
37
References
2010
Year
NanoparticlesNanomedicineDna NanotechnologyMesoporous Silica NanoparticlesEngineeringNanocomplex AssemblyTherapeutic NanomaterialsNanobiotechnologyMedicineSynthetic BiologyShutdown Signaling PathwaysNano-drug DeliveryGene DeliveryBiomedical EngineeringMammalian CellsCell BiologyBiomolecular EngineeringEndogenous Gene Signal
A nanocomplex assembly of polyethylenimine and mesoporous silica nanoparticles are used to successfully protect and deliver siRNA into human cells, effectively shutting down both exogenous and endogenous gene signal.
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