Concepedia

Muscarinic Receptors as Model Targets and Antitargets for Structure-Based Ligand Discovery

Andrew C. Kruse, Dahlia R. Weiss, Mario Rossi, Jianxin Hu, Kelly Hu, Katrin Eitel, Peter Gmeiner, Jürgen Wess, Brian K. Kobilka, Brian K. Shoichet

Molecular Pharmacology · 2013 · 63 citations · 36 references

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36

ChEMBL: a large-scale bioactivity database for drug discovery

Anna Gaulton, Louisa J. Bellis, A. Patrícia Bento et al. · Nucleic Acids Research · 2011 · 4.5K citations · Full text

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ZINC − A Free Database of Commercially Available Compounds for Virtual Screening

John J. Irwin, Brian K. Shoichet · Journal of Chemical Information and Modeling · 2004 · 4.1K citations · Full text

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ZINC: A Free Tool to Discover Chemistry for Biology

John J. Irwin, Teague Sterling, Michael M. Mysinger et al. · Journal of Chemical Information and Modeling · 2012 · 2.6K citations · Full text

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Structure and dynamics of the M3 muscarinic acetylcholine receptor

Andrew C. Kruse, Jianxin Hu, Albert C. Pan et al. · Nature · 2012 · 816 citations

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Structure of the human M2 muscarinic acetylcholine receptor bound to an antagonist

Kazuko Haga, Andrew C. Kruse, Hidetsugu Asada et al. · Nature · 2012 · 795 citations · Full text

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