Activation and allosteric modulation of a muscarinic acetylcholine receptor

Andrew C. Kruse, Aaron M. Ring, Aashish Manglik, +15

Nature

Functional SelectivityMedicineSynaptic TransmissionPhysiologyReceptor (Biochemistry) +4

Structure and dynamics of the M3 muscarinic acetylcholine receptor

Andrew C. Kruse, Jianxin Hu, Albert C. Pan, +11

Nature

BiochemistryG Protein-coupled ReceptorMedicineReceptor (Biochemistry)Neuropharmacology +2

Mammalian Mst1 and Mst2 kinases play essential roles in organ size control and tumor suppression

Hai Song, Kinglun Kingston Mak, Lilia Topol, +11

Proceedings of the National Academy of Sciences

Modulation of tissue repair by regeneration enhancer elements

Junsu Kang, Jianxin Hu, Ravi Karra, +7

Nature

Regenerative MedicineRegenerationEngineeringTissue TransplantationWound Healing +6

Planar cell polarity breaks bilateral symmetry by controlling ciliary positioning

Hai Song, Jianxin Hu, Wen Chen, +4

Nature

BiologyOptogeneticsPattern FormationNeuroanatomyMedicine +11

A mutation in Ihh that causes digit abnormalities alters its signalling capacity and range

Bo Gao, Jianxin Hu, Sigmar Stricker, +9

Nature

Mendelian DisorderGenetic DisorderMedicineGeneticsSignalling Capacity +8

Human Ca2+ Receptor Cysteine-rich Domain

Jianxin Hu, Omar M. Hauache, Allen M. Spiegel

Journal of Biological Chemistry

Identification of Acidic Residues in the Extracellular Loops of the Seven-transmembrane Domain of the Human Ca2+ Receptor Critical for Response to Ca2+ and a Positive Allosteric Modulator

Jianxin Hu, Guadalupe Reyes‐Cruz, Wangzhong Chen, +2

Journal of Biological Chemistry

A Region in the Seven-transmembrane Domain of the Human Ca2+ Receptor Critical for Response to Ca2+

Jianxin Hu, Stuart McLarnon, Stefano Mora, +4

Journal of Biological Chemistry

Effects of a Calcimimetic Compound and Naturally Activating Mutations on the Human Ca²⁺Receptor and on Ca²⁺Receptor/Metabotropic Glutamate Chimeric Receptors

Omar M. Hauache, Jianxin Hu, Kausik K. Ray, +3

Endocrinology

Naturally Activating MutationsSynaptic SignalingCellular PhysiologyMolecular PharmacologyCa2+ Receptor +18