Campylobacter jejuni Induces Acute Enterocolitis in Gnotobiotic IL-10−/− Mice via Toll-Like-Receptor-2 and -4 Signaling

Abstract

Gnotobiotic IL-10(-/-) mice develop acute enterocolitis following C. jejuni infection mimicking severe episodes of human campylobacteriosis and are thus well suited to further dissect mechanisms underlying Campylobacter infections in vivo.