Protein Scaffold Engineering Towards Tunable Surface Attachment

Abstract

Ringing the changes: A selective, controlled, and tunable attachment of proteins to a metal or to insulating surfaces is presented. A ring-shaped protein encapsulating SiO2-binding peptides (see picture: yellow) was engineered to expose multiple binding sites simply by changing solvent conditions, thereby creating a single monolayer without the need for surface modification. Detailed facts of importance to specialist readers are published as ”Supporting Information”. Such documents are peer-reviewed, but not copy-edited or typeset. They are made available as submitted by the authors. Please note: The publisher is not responsible for the content or functionality of any supporting information supplied by the authors. Any queries (other than missing content) should be directed to the corresponding author for the article.