Synthetic Communications · 2009 · 61 citations · 4 references
Natural SciencesChemistryMedicinal ChemistryCatalysisGreen ChemistryReaction EngineeringCatalyst DesignCatalyst PreparationCatalyst SynthesisCatalytic MechanismsCatalytic Reaction EngineeringIndustrial Catalytic ProcessesAqueous Reaction MediaBenzimidazole ChemistryBenzimidazole SynthesisCatalyst Development For SynthesisCatalytic SynthesisChemoselective CatalysisChemoselective SynthesisSustainable Synthesis
Abstract A simple, efficient, and environmentally benign method has been developed for the exclusive formation of biologically significant 2-aryl-1-arylmethyl-1H-benzimidazoles under the heterogeneous catalysis of Amberlite IR-120 in aqueous media in excellent yields. The catalyst is recyclable without loss of activity.
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