Concepedia

Oral Mesalamine (Asacol) for Mildly to Moderately Active Ulcerative Colitis

Charles A. Sninsky, David Cort, Fergus Shanahan, John T. Sessions, Robert E. Pruitt, Walter H. Jacobs, Stephan R. Targan, J J Cerda

Annals of Internal Medicine · 1991 · 208 citations · 20 references

DOI

Abstract

Colon-targeted oral mesalamine at 2.4 g/d is effective therapy for mildly to moderately active ulcerative colitis. It is well tolerated and should provide a viable therapeutic alternative to sulfasalazine.

References

20

Coated Oral 5-Aminosalicylic Acid Therapy for Mildly to Moderately Active Ulcerative Colitis

Kenneth W. Schroeder, William J. Tremaine, Duane M. Ilstrup · New England Journal of Medicine · 1987 · 3K citations

AN EXPERIMENT TO DETERMINE THE ACTIVE THERAPEUTIC MOIETY OF SULPHASALAZINE

A K Azad Khan, J Piris, S. C. Truelove · The Lancet · 1977 · 821 citations

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5-Aminosalicylic acid enema in the treatment of distal ulcerative colitis, proctosigmoiditis, and proctitis

Lloyd R. Sutherland, François Martin, Scott Greer et al. · Gastroenterology · 1987 · 678 citations · Full text

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Adverse Reactions during Salicylazosulfapyridine Therapy and the Relation with Drug Metabolism and Acetylator Phenotype

Kiron M. Das, M. A. Eastwood, J. P. A. McManus et al. · New England Journal of Medicine · 1973 · 449 citations

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THE ROLE OF INTESTINAL BACTERIA IN THE METABOLISM OF SALICYLAZOSULFAPYRIDINE

Mark A. Peppercorn, Peter Goldman · Journal of Pharmacology and Experimental Therapeutics · 1972 · 435 citations