Irreversible Electroporation Ablation: Creation of Large-Volume Ablation Zones in in Vivo Porcine Liver with Four-Electrode Arrays

Abstract

With four-electrode arrays, IRE can create large contiguous zones of treatment effect in clinically acceptable ablation times; parameters can be tailored to achieve a wide range of ablation sizes. Cyclical deposition of IRE application is beneficial, particularly for larger interprobe spacing, most likely owing to alterations of electrical conductivity that occur after successive applications of IRE energy.