Concepedia

Early bactericidal activity of a moxifloxacin and isoniazid combination in smear-positive pulmonary tuberculosis

Stephen H. Gillespie, Roly Gosling, L. Uiso, Noel E. Sam, Esther Kanduma, Timothy D. McHugh

Journal of Antimicrobial Chemotherapy · 2005 · 37 citations · 12 references

DOI

Abstract

The combination of moxifloxacin and isoniazid is not antagonistic, but the combination does not significantly enhance bactericidal activity above that of isoniazid alone.

References

12

The early bactericidal activity of drugs in patients with pulmonary tuberculosis.

Amina Jindani, V R Aber, Eric Edwards et al. · PubMed · 1980 · 498 citations

, , +18

Moxifloxacin-containing Regimen Greatly Reduces Time to Culture Conversion in Murine Tuberculosis

Eric L. Nuermberger, Tetsuyuki Yoshimatsu, Sandeep Tyagi et al. · American Journal of Respiratory and Critical Care Medicine · 2003 · 317 citations

, , +12

Bactericidal and Sterilizing Activities of Antituberculosis Drugs during the First 14 Days

Amina Jindani, Caroline J Doré, D.A. Mitchison · American Journal of Respiratory and Critical Care Medicine · 2003 · 316 citations

, , +19

Moxifloxacin-containing Regimens of Reduced Duration Produce a Stable Cure in Murine Tuberculosis

Eric Nuermberger, Tetsuyuki Yoshimatsu, Sandeep Tyagi et al. · American Journal of Respiratory and Critical Care Medicine · 2004 · 221 citations

, , +16

In Vitro and In Vivo Activities of Moxifloxacin and Clinafloxacin against <i>Mycobacterium tuberculosis</i>

Baohong Ji, Nacer Lounis, Caroline Maslo et al. · Antimicrobial Agents and Chemotherapy · 1998 · 181 citations · Full text