New Therapeutic Approach to Suppress Castration-Resistant Prostate Cancer Using ASC-J9 via Targeting Androgen Receptor in Selective Prostate Cells

Development of a Second-Generation Antiandrogen for Treatment of Advanced Prostate Cancer

Chris Tran, Samedy Ouk, Nicola J. Clegg et al. · Science · 2009 · 2.3K citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +17

Molecular determinants of resistance to antiandrogen therapy

Charlie D. Chen, Derek S. Welsbie, Chris Tran et al. · Nature Medicine · 2003 · 2.3K citations

Medicine, Endocrinology, Urology +17

Mutation of <i>Pten/Mmac1</i> in mice causes neoplasia in multiple organ systems

Katrina Podsypanina, Lora H. Ellenson, Adriana Nemes et al. · Proceedings of the National Academy of Sciences · 1999 · 949 citations · Full text

Veterinary Medicine, Oncology, Pathology +17

Molecular Cloning of Human and Rat Complementary DNA Encoding Androgen Receptors

Chawnshang S. Chang, John M. Kokontis, Shutsung Liao · Science · 1988 · 908 citations

Life Sciences, Biochemistry, Molecular Biology +15

A Novel Androgen Receptor Splice Variant Is Up-regulated during Prostate Cancer Progression and Promotes Androgen Depletion–Resistant Growth

Zhiyong Guo, Xi Yang, Feng Sun et al. · Cancer Research · 2009 · 877 citations · Full text

Medicine, Endocrinology, Oncology +17