2008 · 89 citations · 12 references
ComputingData ScienceMachine LearningStatistical LearningTime Series AnalysisBayesian ComputationBayesian InferenceBayesian LearningBayesian Model BuildingBayesian StatisticsMarkov Chain Monte CarloBayesian Graphical ModelsBayesian Network Structure LearningBayesian NetworksConditional Dependence EstimationConditional StructureDependence StructureGraphical Model Structure LearningGraphical Models
A principled mechanism for identifying conditional dependencies in time-series data is provided through structure learning of dynamic Bayesian networks (DBNs). An important assumption of DBN structure learning is that the data are generated by a stationary process—an assumption that is not true in many important settings. In this paper, we introduce a new class of graphical models called non-stationary dynamic Bayesian networks, in which the conditional dependence structure of the underlying data-generation process is permitted to change over time. Non-stationary dynamic Bayesian networks represent a new framework for studying problems in which the structure of a network is evolving over time. We define the non-stationary DBN model, present an MCMC sampling algorithm for learning the structure of the model from time-series data under different assumptions, and demonstrate the effectiveness of the algorithm on both simulated and biological data. 1
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Using Bayesian Networks to Analyze Expression Data
Nir Friedman, Michal Linial, Iftach Nachman et al. · Journal of Computational Biology · 2000 · 3.3K citations
Gene Expression During the Life Cycle of <i>Drosophila melanogaster</i>
Michelle N Arbeitman, Eileen E. M. Furlong, Farhad Imam et al. · Science · 2002 · 946 citations