Cooperative Catalysis by Ru and Pd for the Direct Coupling of a Chelating Aldehyde with Iodoarenes or Organostannanes

Abstract

Two is better than one: The combination of two metallic catalyst systems effects transformations that are difficult to carry out with any single-catalyst systems. This is demonstrated by the coupling of 8-quinolinecarboxaldehyde with a range of iodoarenes to give diaryl ketones (see picture) and its reaction with organostannanes to afford ketones.