The tim Mutant of the Drosophila Rhythm Gene timeless Manifests Allele-Specific Interactions with period Gene Mutants

Clock Mutants of <i>Drosophila melanogaster</i>

Ronald J. Konopka, Seymour Benzer · Proceedings of the National Academy of Sciences · 1971 · 2.3K citations · Full text

Life Sciences, Entomology, Genetics +17

Cdi1, a human G1 and S phase protein phosphatase that associates with Cdk2

Jenő Gyuris · Cell · 1993 · 1.5K citations

Life Sciences, Cell Biology, Molecular Biology +11

Feedback of the Drosophila period gene product on circadian cycling of its messenger RNA levels

Paul E. Hardin, Jeffrey C. Hall, Michael Rosbash · Nature · 1990 · 1.2K citations

Life Sciences, Genetics, Molecular Biology +16

Loss of Circadian Behavioral Rhythms and <i>per</i> RNA Oscillations in the <i>Drosophila</i> Mutant <i>timeless</i>

Amita Sehgal, Jeffrey L. Price, Bernice Man et al. · Science · 1994 · 660 citations

Life Sciences, Genetics, Molecular Genetics +17

Negative Feedback Defining a Circadian Clock: Autoregulation of the Clock Gene <i>frequency</i>

Benjamin D. Aronson, Keith A. Johnson, Jennifer Loros et al. · Science · 1994 · 610 citations

Life Sciences, Genetics, Molecular Biology +15