Concepedia

High-salt diet increases glomerular ACE/ACE2 ratio leading to oxidative stress and kidney damage

Stella Bernardi, Barbara Toffoli, Cristina Zennaro, Christos Tikellis, Silvia Monticone, Pasquale Losurdo, Giuseppe Bellini, Merlin C. Thomas, Francesco Fallo, Franco Veglio,

Nephrology Dialysis Transplantation · 2011 · 80 citations · 30 references

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Abstract

One of the mechanisms by which a high-salt diet leads to renal damage seems to be the modulation of the ACE/ACE2 ratio which in turn is critical for the cause of oxidative stress, through AngII.

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30

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