Parallel increase in community use of fosfomycin and resistance to fosfomycin in extended-spectrum -lactamase (ESBL)-producing Escherichia coli

Abstract

Key factors related to increased fosfomycin resistance in ESBL-EC causing UTIs could be the rapid growth in community use of fosfomycin, the widespread distribution of the 025b/B2 E. coli clone and the existence of a susceptible population comprising women residing in nursing home facilities.