Bronchodilatory and anti-inflammatory properties of inhaled selective phosphodiesterase inhibitors in a guinea pig model of allergic asthma

Molecular cloning and characterization of a distinct human phosphodiesterase gene family: PDE11A

Lindsay Fawcett, Rhona W. Baxendale, Peter Stacey et al. · Proceedings of the National Academy of Sciences · 2000 · 360 citations

The specific type IV phosphodiesterase inhibitor rolipram suppresses tumor necrosis factor-α production by human mononuclear cells

J. Semmler, H. Wachtell, Stefan Endres · International Journal of Immunopharmacology · 1993 · 221 citations

Inflammation, Thrombopoiesis, Anti-inflammatory +8

Identification, characterization and functional role of phosphodiesterase isozymes in human airway smooth muscle.

Theodore J. Torphy, Bradley J. Undem, L B Cieslinski et al. · Journal of Pharmacology and Experimental Therapeutics · 1993 · 165 citations

Inhibition of eosinophil cyclic nucleotide PDE activity and opsonised zymosan‐stimulated respiratory burst by ‘type IV’‐selective PDE inhibitors

Gordon Dent, Mark A. Giembycz, Klaus F. Rabe et al. · British Journal of Pharmacology · 1991 · 141 citations · Full text

Human bronchial cyclic nucleotide phosphodiesterase isoenzymes: biochemical and pharmacological analysis using selective inhibitors

J. de Boer, Alison J. Philpott, Ronald G.M. van Amsterdam et al. · British Journal of Pharmacology · 1992 · 129 citations · Full text

Asthma, Pharmaceutical Science, Phosphodiesterase Isoenzymes +17