Highly Selective Palladium‐Catalyzed Oxidative C<i>sp</i>²C<i>sp</i>³ Cross‐Coupling of Arylzinc and Alkylindium Reagents through Double Transmetallation

Abstract

Abstract magnified image Using desyl chloride (2‐chloro‐1,2‐diphenylethanone) as the oxidant, the palladium‐catalyzed reaction of arylzinc with alkylindium reagents occurred smoothly in a highly selective manner to afford the products in 57–90% yields. Preliminary kinetic data indicated that alkylindium reagents were highly favored for transmetallation with the alkoxy‐palladium moiety.