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Publication | Open Access

Effects of Native and Myeloperoxidase-Modified Apolipoprotein A-I on Reverse Cholesterol Transport and Atherosclerosis in Mice

DOIFull Paper Access

144

Citations

48

References

2014

Year

Bernd Hewing, Saj Parathath, Tessa J. Barrett, Wing Ki Kellie Chung, Yaritzy M. Astudillo, Tadateru Hamada, Bhama Ramkhelawon, Thomas C. Tallant, Mohamed Shaif S. Yusufishaq, Joseph A. DiDonato,
Arteriosclerosis Thrombosis and Vascular Biology

Abstract

Myeloperoxidase-mediated oxidation renders ApoA-I dysfunctional and unable to (1) promote reverse cholesterol transport, (2) mediate beneficial changes in the composition of atherosclerotic plaques, and (3) pacify the inflammatory status of plaque macrophages.

References

YearCitations

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