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Spectrophotometric determination of oxygen saturation of blood independent of the presence of indocyanine green
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1979
Year
Absorption SpectroscopyStrong AbsorbanceOxygen SaturationChemistryOxidative StressBioanalysisAnalytical ChemistryClinical ChemistryPhotosynthesisPhotophysical PropertyBiophysicsChromatographyHealth SciencesSpectrophotometric DeterminationPhotochemistryBiochemistryUv-vis SpectroscopyIndocyanine GreenSpectroscopyPhysiologyTissue OxygenationLight AbsorptionMedicineGreen Analytical MethodPigment
The strong absorbance of indocyanine green in a broad band around lambda = 800 nm invalidates the usual spectrophotometric two-wavelength methods for measuring oxygen saturation operating in the red and near infrared region. By proper wavelength selection, however, the effect of the dye can be eliminated. With the two-wavelength method utilising lambda = 660 and 860 nm oxygen saturation is measured virtually independent of the presence of indocyanine green.