Korean Diabetes Journal · 2008 · 10 citations · 20 references
MedicineEndocrinologyBehavioral MedicineBehavioral PharmacologyDiabetologyDiabetes ControlDiabetes ManagementDiabetes MellitusGlycemic ControlInsulin ResistanceInsulin TherapyInsulin ManagementInsulin Resistance SyndromeOral Hypoglycemic TherapyPsychological BarriersReluctanceTight Glycemic ControlType 2 Diabetes Mellitus TreatmentType 2 Diabetes Treatment
Background: To achieve tight glycemic control in the poorly controlled type 2 diabetic patients with oral hypoglycemic agent, it maybe beneficial to initiate insulin treatment at the early stage. Many patients with type 2 diabetes are often reluctant to begin insulin therapy despite poor glycemic control with oral hypoglycemic agents, this little known phenomenon, often termed 'psychological insulin resistance (PIR)'.
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Yasuo Ohkubo, Hideki Kishikawa, Eiichi Araki et al. · Diabetes Research and Clinical Practice · 1995 · 3.1K citations