Toward development of a non-viral gene therapeutic

A versatile vector for gene and oligonucleotide transfer into cells in culture and in vivo: polyethylenimine.

Otmane Boussif, Frank Lezoualc’h, Maria Antonietta Zanta et al. · Proceedings of the National Academy of Sciences · 1995 · 6.2K citations

Pharmacy, Biotechnology, Pharmaceutics +17

Lipofection: a highly efficient, lipid-mediated DNA-transfection procedure.

Philip L. Felgner, Thomas R. Gadek, Mai Marie Holm et al. · Proceedings of the National Academy of Sciences · 1987 · 5K citations · Full text

Life Sciences, Biotechnology, Molecular Biology +15

Direct Gene Transfer into Mouse Muscle in Vivo

Jon A. Wolff, Robert W. Malone, Phillip Williams et al. · Science · 1990 · 4.2K citations

Life Sciences, Genetics, Molecular Biology +16

Cellular immunity to viral antigens limits E1-deleted adenoviruses for gene therapy.

Yang Yang, Frederick A. Nunes, Klára Berencsi et al. · Proceedings of the National Academy of Sciences · 1994 · 1.6K citations

Life Sciences, Immunology, Molecular Biology +15

Cellular and Molecular Barriers to Gene Transfer by a Cationic Lipid

Joseph Zabner, A Fasbender, Tom Moninger et al. · Journal of Biological Chemistry · 1995 · 1.4K citations · Full text

Pharmacy, Biotechnology, Molecular Biology +16