Concepedia

Adenovirus-Mediated Heme Oxygenase-1 Gene Delivery Inhibits Injury-Induced Vascular Neointima Formation

David A. Tulis, William Durante, Xiaoming Liu, Alida J. Evans, Kelly J. Peyton, Andrew I. Schafer

Circulation · 2001 · 164 citations · 27 references

Abstract

These results indicate that HO-1 represents an important in vivo vasoprotective mediator that is capable of attenuating the pathophysiological remodeling response to endovascular injury and suggest that HO-1 may be a novel target for the treatment of vascular disease.

References

27

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