Expression of Fas/FasL in CD8⁺T and CD3⁺Foxp3⁺Treg Cells - Relationship with Apoptosis of Circulating CD8⁺T Cells in Hepatocellular Carcinoma Patients

Abstract

Fas/FasL interactions might lead to excessive turnover of CD8+T cells and reduce anti-tumor immune responses in patients with HCC. Further investigations of apoptosis induction in Fas+CD8+T cells in vitro are required.