<i>p53</i> Gene and Protein Status: The Role of <i>p53</i> Alterations in Predicting Outcome in Patients With Bladder Cancer

Abstract

We show that evaluation of both the p53 gene and protein statuses provides information in assessing the clinical recurrence risk in bladder cancer and that the specific mutation site may be important in assessing recurrence risk. These findings may substantially impact the assessment of p53 alterations and the management of bladder cancer.