Publication | Open Access
<i>Campylobacter jejuni</i>CsrA Mediates Oxidative Stress Responses, Biofilm Formation, and Host Cell Invasion
141
Citations
60
References
2008
Year
Biofilm FormationBiochemistryMicrobial PathogensHost Cell InvasionMedicinePathogenesisVirulence FactorCampylobacter InfectionsCsra MutantC. Jejuni PathogenesisMicrobiologyGut BarrierMolecular MicrobiologyHost-microbe InteractionBacterial PathogensClinical MicrobiologyRedox BiologyOxidative Stress
The putative global posttranscriptional regulator csrA was mutated in Campylobacter jejuni 81-176. The csrA mutant was attenuated in surviving oxidative stress. CsrA also contributed to biofilm formation and adherence to and invasion of INT407 intestinal epithelial cells, suggesting a regulatory role for CsrA in C. jejuni pathogenesis.
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