Concepedia

A Facile Synthesis of the Basic Steroidal Skeleton Using a Pauson−Khand Reaction as a Key Step

Do Han Kim, Kwang J. Kim, Young Keun Chung

The Journal of Organic Chemistry · 2006 · 19 citations · 19 references

DOI

Concepts

Abstract

A high-yield synthesis of steroid-type molecules under mild reaction conditions is achieved in two steps involving nucleophilic addition of alkynyl cerium reagent to an easily enolizable carbonyl compound (beta-tetralone) followed by an intramolecular Pauson-Khand reaction.

References

19

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A Pauson−Khand-Type Reaction between Alkynes and Olefinic Aldehydes Catalyzed by Rhodium/Cobalt Heterobimetallic Nanoparticles:  An Olefinic Aldehyde as an Olefin and CO Source

Kang Hyun Park, Il Gu Jung, Young Keun Chung · Organic Letters · 2004 · 67 citations

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