Concepedia

Reduction in Neural-Tube Defects after Folic Acid Fortification in Canada

Philippe De Wals, Fassiatou Tairou, Margot I. Van Allen, Soo-Hong Uh, R. Brian Lowry, Barbara Sibbald, Jane Evans, Michiel C. Van den Hof, Pamela Zimmer, Marian Crowley,

New England Journal of Medicine · 2007 · 837 citations · 26 references

DOI

Abstract

Food fortification with folic acid was associated with a significant reduction in the rate of neural-tube defects in Canada. The decrease was greatest in areas in which the baseline rate was high.

References

26

Prevention of Neural-Tube Defects with Folic Acid in China

R. J. Berry, Jon D. Erickson, Cynthia A. Moore et al. · New England Journal of Medicine · 1999 · 1.3K citations · Full text

Prevention of Neural-Tube Defects with Folic Acid in China

Caren Contact · New England Journal of Medicine · 1999 · 1.1K citations · Full text

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Folate and vitamin B-12 status in relation to anemia, macrocytosis, and cognitive impairment in older Americans in the age of folic acid fortification

Martha Savaria Morris, Paul F. Jacques, Irwin H. Rosenberg et al. · American Journal of Clinical Nutrition · 2007 · 599 citations

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Risk of Neural Tube Defect—Affected Pregnancies Among Obese Women

Gary M. Shaw · JAMA · 1996 · 348 citations

Association of neural tube defects and folic acid food fortification in Canada

Joel G. Ray, Chris Meier, Marian J. Vermeulen et al. · The Lancet · 2002 · 294 citations

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