Mitochondria Protection with Ginkgolide B-Loaded Polymeric Nanocapsules Prevents Diethylnitrosamine-Induced Hepatocarcinoma in Rats

Abstract

Positive zeta-potential on N2GB surface might have offered higher hepatic accumulation of GB, especially at the electron-dense organelle mitochondria. Mitochondria protection against DEN-induced oxidative damage ensured HCC prevention.