Hollow Manganese Oxide Nanoparticles as Multifunctional Agents for Magnetic Resonance Imaging and Drug Delivery

Abstract

MRI jack-o'-lanterns? Hollow manganese oxide nanoparticles (HMON) show greatly improved relaxivities and drug-loading capacities compared to those with solid interiors (WMON). Their efficient cellular uptake demonstrates their potential as a bifunctional medical system that combines diagnostic imaging and targeted therapy.