Concepedia

Systemic Exposure to the Metabolites of Lesogaberan in Humans and Animals: A Case Study of Metabolites in Safety Testing

Ann Aurell Holmberg, Anja Ekdahl, Lars Weidolf

Drug Metabolism and Disposition · 2014 · 13 citations · 9 references

DOI

Concepts

References

9

Gastroesophageal Reflux Disease

P. J. Kahrilas · JAMA · 1996 · 567 citations

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Approach to hydrophilic interaction chromatography column selection: Application to neurotransmitters analysis

Raluca-Ioana Chirita, Caroline West, A.-L. Finaru et al. · Journal of Chromatography A · 2010 · 119 citations

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Effects of Lesogaberan on Reflux and Lower Esophageal Sphincter Function in Patients With Gastroesophageal Reflux Disease

Guy E. Boeckxstaens, Hanneke Beaumont, Veerle Mertens et al. · Gastroenterology · 2010 · 108 citations · Full text

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Best Practices in a Tiered Approach to Metabolite Quantification: Views and Recommendations of The European Bioanalysis Forum

Philip Timmerman, Morten A. Kall, Ben Gordon et al. · Bioanalysis · 2010 · 83 citations

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A novel reflux inhibitor lesogaberan (AZD3355) as add-on treatment in patients with GORD with persistent reflux symptoms despite proton pump inhibitor therapy: a randomised placebo-controlled trial

Guy E. Boeckxstaens, Hanneke Beaumont, Jan Gunnar Hatlebakk et al. · Gut · 2011 · 81 citations · Full text

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