Group 2 innate lymphoid cells (<scp>ILC</scp>2s) are increased in chronic rhinosinusitis with nasal polyps or eosinophilia

Abstract

As ILC2s are elevated in patients with CRSwNP, they may drive nasal polyp formation in CRS. ILC2s are also linked with high tissue and blood eosinophilia and have a potential role in the activation and survival of eosinophils during the Th2 immune response. The association of innate lymphoid cells in CRS provides insights into its pathogenesis.