Hepatic methotrexate content and progression of hepatic fibrosis: preliminary findings.

Methotrexate metabolism analysis in blood and liver of rheumatoid arthritis patients: Association with hepatic folate deficiency and formation of polyglutamates

Joel M. Kremer, John Galivan, Anita Streckfuss et al. · Arthritis & Rheumatism · 1986 · 214 citations

Medicine, Pharmacokinetics, Pharmacology +15

Liver histology in rheumatoid arthritis patients receiving long‐term methotrexate therapy. A Prospective Study with Baseline and Sequential Biopsy Samples

Joel M. Kremer, Randall G. Lee, Keith G. Tolman · Arthritis & Rheumatism · 1989 · 199 citations

Medicine, Internal Medicine, Pharmacology +15

Methotrexate Hepatotoxicity in Psoriasis—Comparison of Different Dose Regimens

M.G.C. Dahl, M. M. Gregory, Peter J. Scheuer · BMJ · 1972 · 178 citations · Full text

Medicine, Pharmacology, Pharmacotherapy +8

Methotrexate in rheumatoid arthritis

Daniel E. Fürst, Joel M. Kremer · Arthritis & Rheumatism · 1988 · 165 citations

Medicine, Pharmacokinetics, Pharmacology +14

Methotrexate Accumulation and Folate Depletion in Cells as a Possible Mechanism of Chronic Toxicity to the Drug

B A Kamen, Patricia A. Nylen, Bruce M. Camitta et al. · British Journal of Haematology · 1981 · 115 citations

Pharmacy, Pharmacology, Toxicology +17