Development and Automation of a 384-Well Cell Fusion Assay to Identify Inhibitors of CCR5/CD4-Mediated HIV Virus Entry

Sensitivity of HIV-1 to entry inhibitors correlates with envelope/coreceptor affinity, receptor density, and fusion kinetics

Jacqueline D. Reeves, Stephen A. Gallo, Navid Ahmad et al. · Proceedings of the National Academy of Sciences · 2002 · 403 citations · Full text

Clinical manifestations and management of antiretroviral nucleoside analog-related mitochondrial toxicity

Graeme Moyle · Clinical Therapeutics · 2000 · 194 citations

Mitochondrial Function, Medicine, Neurovirology +6

Discovery of Novel, Potent, and Selective Small-Molecule CCR5 Antagonists as Anti-HIV-1 Agents:  Synthesis and Biological Evaluation of Anilide Derivatives with a Quaternary Ammonium Moiety

Mitsuru Shiraishi, Yoshio Aramaki, Masaki Seto et al. · Journal of Medicinal Chemistry · 2000 · 185 citations · Full text

Lead Compounds, Cho/ccr5 Cells, Lead Identification +19

Constitutive cell surface association between CD4 and CCR5

Xiaodong Xiao, Lijun Wu, Tzanko S. Stantchev et al. · Proceedings of the National Academy of Sciences · 1999 · 177 citations · Full text

A screening assay for antiviral compounds targeted to the HIV-1 gp41 core structure using a conformation-specific monoclonal antibody

Shibo Jiang, Lin Kang, Li Zhang et al. · Journal of Virological Methods · 1999 · 109 citations

Biochemistry, Natural Sciences, Antiviral Compounds +12