LaCl₃ · 7H₂O‐Promoted Regioselective Ring Opening of Epoxides Using NaNO₂in Ether–Water System: A Facile Synthesis of 2‐Nitroalcohols

Abstract

Abstract A convenient and efficient synthesis of 2‐nitroalcohols has been achieved by regioselective ring opening of epoxides using LaCl3 · 7H2O and NaNO2 in ether–H2O system at room temperature. The reaction afforded the corresponding products in good to excellent yields under mild conditions. Keywords: 2‐Nitroalcoholsepoxidesphase‐transfer catalystring openingsodium nitrite Acknowledgment The authors gratefully acknowledge the Director, Regional Research Laboratory (CSIR), Jorhat, Assam, India, for providing facilities for this work. S. G. and J. B. thank CSIR, New Delhi, for the award of Senior Research Fellowship.