Concepedia

Characterization of a selective inhibitor of the Parkinson's disease kinase LRRK2

Xianming Deng, Nicolas Dzamko, Alan R. Prescott, Paul Davies, Qingsong Liu, Qingkai Yang, Jiing‐Dwan Lee, Matthew P. Patricelli, Tyzoon Nomanbhoy, Dario R. Alessi,

Nature Chemical Biology · 2011 · 431 citations · 20 references

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PD 098059 Is a Specific Inhibitor of the Activation of Mitogen-activated Protein Kinase Kinase in Vitro and in Vivo

Dario R. Alessi, Ana Cuenda, Philip Cohen et al. · Journal of Biological Chemistry · 1995 · 3.4K citations · Full text

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Anorexigenic and Orexigenic Hormone Modulation of Mammalian Target of Rapamycin Complex 1 Activity and the Regulation of Hypothalamic Agouti-Related Protein mRNA Expression

Kenneth R. Watterson, Dawn Bestow, Jennifer Gallagher et al. · Neurosignals · 2012 · 3.4K citations · Full text

, , +17

A specific inhibitor of phosphatidylinositol 3-kinase, 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one (LY294002).

Chris J. Vlahos, William F. Matter, K. Y. Hui et al. · Journal of Biological Chemistry · 1994 · 3.3K citations · Full text

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Mutations in LRRK2 Cause Autosomal-Dominant Parkinsonism with Pleomorphic Pathology

Alexander Zimprich, Saskia Biskup, Petra Leitner et al. · Neuron · 2004 · 3.1K citations · Full text

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The selectivity of protein kinase inhibitors: a further update

Jenny Bain, Lorna Plater, Matt Elliott et al. · Biochemical Journal · 2007 · 2.5K citations · Full text

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