Pan-American mDNA haplogroups in Chilean patients with Leber's hereditary optic neuropathy.

Abstract

In this limited sample size, the Amerindian haplogroup A2 was associated with delayed onset of disease in this population. Patients with haplogroup C retained better vision than the patients with other haplogroups in this population. Disease in subjects with haplogroup D appeared to be underrepresented compared to the population at large.