Concepedia

Exclusive formation of imino[4 + 4]cycloaddition products with biologically relevant amines: plausible candidates for acrolein biomarkers and biofunctional modulators

Ayumi Tsutsui, Ambara R. Pradipta, E. Sh. Saigitbatalova, Almira R. Kurbangalieva, Katsunori Tanaka

MedChemComm · 2014 · 22 citations · 41 references

DOI

Concepts

Abstract

We synthetically demonstrate that eight-membered heterocycles are the exclusive products of the reaction of acrolein with biologically relevant amines<italic>via</italic>an imino[4 + 4]cycloaddition.

References

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