Concepedia

Regular Transfusion Lowers Plasma Free Hemoglobin in Children With Sickle-Cell Disease at Risk for Stroke

Nelson Lezcano, Nadine Odo, Abdullah Kutlar, Donald Brambilla, Robert J. Adams

Stroke · 2006 · 87 citations · 10 references

DOI

Abstract

Regular transfusion which lowers stroke risk is associated with a significant reduction in PFH. A role for PFH in promoting stroke in SCD should be investigated.

References

10

Prevention of a First Stroke by Transfusions in Children with Sickle Cell Anemia and Abnormal Results on Transcranial Doppler Ultrasonography

Robert J. Adams, Lewis L. Hsu, Elliott Vichinsky et al. · New England Journal of Medicine · 1998 · 1.8K citations · Full text

Cerebrovascular accidents in sickle cell disease: rates and risk factors.

Kwaku Ohene‐Frempong, Steven J. Weiner, Lynn A. Sleeper et al. · PubMed · 1998 · 1.7K citations

PREVENTION OF A FIRST STROKE BY TRANSFUSIONS IN CHILDREN WITH SICKLE CELL ANEMIA AND ABNORMAL RESULTS ON TRANSCRANIAL DOPPLER ULTRASONOGRAPHY

R Obert J. A Dams, V Irgil C. M C K Ie, L Ewis H Su et al. · 2015 · 1.3K citations

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Cell-free hemoglobin limits nitric oxide bioavailability in sickle-cell disease

Christopher D. Reiter, Xunde Wang, José E. Tanus‐Santos et al. · Nature Medicine · 2002 · 1.1K citations

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Cell-free hemoglobin limits nitric oxide bioavailability in sickle-cell disease

Christopher D. Reiter, Xunde Wang, José E. Tanus‐Santos et al. · Nature Medicine · 2002 · 1.1K citations

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